[Home ] [Archive]   [ فارسی ]  
:: Home About Conference Registration Article Submission Contact us Site Map ::
:: Volume 1 - ::
3 2021, 1 - : 0-0 Back to browse issues page
Burden of Alzheimer's disease and other dementias in elderly people in Asia: a systematic analysis for the Global Burden of Disease Study in 2019
Zaher Khazaei, Elham Goodarzi *
Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran
Abstract:   (82 Views)
 
Background and Objective: Alzheimerchr('39')s disease (AD) is a progressive and damaging brain disease of unknown etiology. The goal of this study is to investigate the burden of AD in Asia in 2019.
 
Materials and Methods: All data sources accessible from the 2019 Global Burden of Disease study were used to estimate prevalence, mortality and disability-adjusted life years of the Alzheimerchr('39')s disease and other dementias as well as Alzheimerchr('39')s disease’s attributable risk factors in Asia from 1990 to 2019. We estimated all-cause and cause-specific mortality, years of life lost (YLLs), years lived with disability (YLDs), disability-adjusted life-years (DALYs) and attributable risks. All estimates were presented as counts and age-standardized rates per 100,000 population with uncertainty intervals (UIs).
 
Findings: The highest incidence, prevalence, mortality, burden of disease, YLL and YLD belonged to high-income areas and the lowest to middle-income areas. There is a positive and significant correlation between human development index (HDI) and disease incidence (r = 0.319, P<0.05) and the prevalence of the disease (r=0.325, P <0.05). The results revealed a positive and significant correlation between HDI and disease burden (DALY) in women (r = 0.325, P <0.05). There is also a positive and significant correlation between HDI and YLD in both sexes (r = 0.414, P <0.05). However, no positive and significant correlation was found between HDI and YLL (P> 0.05). There incidence of AD in the elderly was positively and significantly related to the mean years of schooling (r = 0.428, P <0.05). Also, life expectancy at birth was positively and significantly correlated with the burden of disease (DALY) (r = 0.362, P <0.05) and YLL (r = 0.317, P <0.05). The results also illustrated a positive and significant correlation between YLD and mean years of schooling (r = 0.510, P <0.05) life expectancy at birth (r = 0.397, P <0.05) and expected years of schooling (r = 0.399, P <0.05).
 
Conclusion: These estimates can be used to guide the elderly care planning and interventions. Hence, policymakers and health care providers need to be informed of these trends to provide appropriate services.
 
Keywords: Dementia, Alzheimer’s disease, Burden disease, DALY, Elderly
     
Type of Study: Research | Subject: General
Received: 2021/07/18 | Accepted: 2021/07/21 | Published: 2021/08/1
فایل پوستر [PPT 362 KB]  (8 Download)
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

khazaei Z, goodarzi E. Burden of Alzheimer's disease and other dementias in elderly people in Asia: a systematic analysis for the Global Burden of Disease Study in 2019. 3. 2021; 1
URL: http://elderhealth.jmu.ac.ir/article-1-184-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 1 - Back to browse issues page
همایش ملی سلامت سالمندی National Conference on Elderly Health
Persian site map - English site map - Created in 0.09 seconds with 31 queries by YEKTAWEB 4341